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Jnk2 Monoclonal Antibody (12C5)

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
Jnk2 Monoclonal Antibody (12C5) 100 µg   905-648 $375.00
Background
The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinase belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.

Table of Abbreviations

Applications
EIA, IHC, WB

Species Reactivity
H, M, C

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic peptide derived from sequence near the amino terminus of Jnk2, conjugated to hemocyanin

Host
Mouse

Clone Number
12C5

Positive Control
Untreated A431 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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