Creatinine Colorimetric Detection Kit

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Description Size Catalog# Price Quantity  
Creatinine Colorimetric Detection Kit 10x96 well   937-001 $695.00
Background
Creatinine (2-amino-1-methyl-5H-imadazol-4-one) is a metabolite of phosphocreatine (p-creatine), a molecule used as a store for high-energy phosphate that can be utilized by tissues for the production of ATP. Creatine either comes from the diet or is synthesized from the amino acids arginine, glycine, and methionine. This occurs in the kidneys and liver, although other organ systems may be involved and species-specific differences may exist. Creatine and p-creatine are converted non-enzymatically to the metabolite creatinine, which diffuses into the blood and is excreted by the kidneys. In vivo, this conversion appears to be irreversible and in vitro it is favored by higher temperatures and lower pH. Creatinine forms spontaneously from p-creatine, and under normal conditions, its formation occurs at a relatively constant rate. Intra-individual variation of creatinine levels is <15% from day to day, making it a useful marker for normalizing levels of other molecules found in urine. Altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.

Table of Abbreviations

Applications
Quantitation / Detection

Species Reactivity
Species Independent

Features

  • Easy-to-use - novel one-step creatinine detection
  • Fast - homogeneous mix-and-ready assay with no wash steps
  • Accurate - calibrated to NIST creatinine standard

Product Image(s): click to enlarge

Range
0.31 - 20 mg/dL

Sensitivity
0.019 mg/dL

Sample Types
urine

Time To Answer
30 minutes

For research use only, not for diagnostic or therapeutic use.

Documentation
Insert

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Citations
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Ordering Info
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