Hsp40 (Hdj1) Monoclonal Antibody (2E1)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsp40 (Hdj1) Monoclonal Antibody (2E1) 100 µg  SPA-450E $295.00
Background
Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.

Table of Abbreviations

Abbreviated Name
Hsp40 mAb (2E1)

Conjugate

Applications
IP, WB

Isotype
IgG2a

Purification
Protein A Affinity

Immunogen
Recombinant human Hsp40 (Hdj1)

Product Image(s): click to enlarge

Host
Mouse

Clone Number
2E1

PositiveControls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
H, M

For research use only, not for diagnostic or therapeutic use.

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