iNOS Polyclonal Antibody

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Description Size Catalog# Price Quantity  
iNOS Polyclonal Antibody   1.0 mL 905-431 $295.00  
Background
Nitric oxide (NO) is synthesized from L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthases (NOS I-III). Analysis of cDNA clones has identified three distinct NOS genes in mammals: neuronal (nNOS/NOS-I), endothelial (eNOS/NOS-III), and inducible (iNOS/NOS-II). eNOS and nNOS are constitutively expressed, agonist-triggered, Ca2+/calmodulin-dependent, and are inhibited by L-arginine analogues (L-NNA, L-NMMA). They are expressed in endothelium, adrenal glands, brain, and platelets. iNOS is inducible, Ca2+/calmodulin-independent, and also inhibited by NMMA and L-NNA. It is expressed in macrophages, hepatocytes, tumor cells, vascular smooth muscle and endothelial cells.

Table of Abbreviations

Applications
IHC

Species Reactivity
H, M, R

Conjugate

Isotype
not applicable

Purification
Affinity Purified

Immunogen
Synthetic peptide derived from a sequence near the carboxy-terminus of mouse iNOS

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

For research use only, not for diagnostic or therapeutic use.

Documentation

Product Manual

Product Name Catalog # Manual
iNOS Polyclonal Antibody 905-431   Spec Sheet    

Related Products

Product Name Catalog#
eNOS Polyclonal Antibody
905-386
iNOS Polyclonal Antibody
KAS-NO001
iNOS Polyclonal Antibody
KAS-NO001D
iNOS Polyclonal Antibody
KAS-NO001F

Citations
Launch Citation Database

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