Substrates & Inhibitors

substrates and inhibitorsAssay DesignsTM provides a variety of inhibitors and kinase substrates for the study of key signaling proteins and pathways. Select from our list of common protein modification and folding inhibitors, including kinase, phosphatase, glycosylase, and heat shock protein inhibitors. We also offer protein kinase substrates suitable for use in kinase assays, including substrates for Akt, Erk, PKC, p70 S6K, and more.

Image: Hsp90 in complex with Geldanamycin
Inhibitor(19)
Protein Kinase Substrate(11)
Substrate(3)
    showing 1 - 33 of 33  
Description Application Species Reactivity Catalog #
Stop Solution 2, 50 mL EIA 80-1804
TMB Substrate, 10 mL Colorimetric EIA/ELISA HRP substrate 80-0350
TMB Substrate, 50 mL EIA 80-1805
Thapsigargin, ER Inhibitor Inhibits SERCA; Induces UPR Species Independent 908-298
Tunicamycin, N-linked glycosylation Inhibitor Inhibits protein glycosylation, arrests cell cycle in late G1, unstable at acidic pH, product is not sterile Species Independent 908-297
14-22 Amide (Myristoylated), PKA Inhibitor PKA Inhibition Species Independent HPK-108I
17-AAG, Hsp90 Inhibitor Hsp90 Inhibition Species Independent HPK-101J
17-DMAG, Hsp90 Inhibitor Hsp90 Inhibition Not applicable HPK-118J
17-GMB-APA-GA, Hsp90 Inhibitor Hsp90 Inhibition Not applicable HPK-119J
Akt (PKB) / SGK Substrate Protein Kinase Substrate Species Independent SPK-103J
Casein Kinase 1 Substrate Protein Kinase Substrate Species Independent SPK-106J
Casein Kinase 2 Substrate Protein Kinase Substrate Species Independent SPK-107J
Crebtide Substrate Protein Kinase Substrate Species Independent SPK-102J
Crosstide Substrate KA Species Independent SPK-108J
Erktide Substrate Protein Kinase Substrate Species Independent SPK-111J
Geldanamycin, Hsp90 Inhibitor Hsp90 Inhibition Species Independent HPK-102J
Genistein, Tyrosine Kinase Inhibitor Tyrosine Kinase Inhibitor Species Independent HPK-103N
H-89, PKA Inhibitor PKA Inhibition Species Independent HPK-105L
Kemptide Substrate KA Species Independent SPK-101J
LY-294002, PI3 Kinase Inhibitor PI3-K Inhibition Species Independent HPK-106L
MG-132, Proteasome Inhibitor Proteasome Species Independent HPK-116L
Okadaic Acid, Phosphatase Inhibitor Phosphatase Inhibition Species Independent HPK-117C
PD-98059 (2'-Amino-3'-methoxyflav.), MEK Inhibitor MEK Inhibition Species Independent HPK-107L
PKC Substrate KA Species Independent SPK-104J
Rapamycin, Inhibitor FK506 binding protein Inhibition Species Independent HPK-109J
SB-203580, p38 MAP kinase Inhibitor p38 MAP Kinase Inhibition Species Independent HPK-110J
SGKtide Substrate KA Species Independent SPK-110J
SP600125, Jnk Inhibitor Jnk Inhibition Species Independent HPK-111M
Src/Lck Substrate KA Species Independent SPK-105J
Staurosporine, Kinase Inhibitor Kinase Inhibition Species Independent HPK-112E
U-0126, MEK Inhibitor MEK Inhibition Species Independent HPK-113J
Wortmannin, PI3 Kinase Inhibitor PI3-K Inhibition Species Independent HPK-114J
p70 S6K (Rsk) Substrate KA Species Independent SPK-109J
    showing 1 - 33 of 33