Opioid Receptor kappa Polyclonal Antibody

Brand: Proteimax Print Page
Description Size Catalog# Price Quantity  
Opioid Receptor kappa Polyclonal Antibody 100 µg  905-799-100 $295.00
Background
The opioid receptors delta (DOP, OP1), kappa (KOP, OP2), and mu (MOP, OP3) are members of the seven-transmembrane domain-containing receptor family of G-protein coupled receptors, sharing nearly 60% identity, but varying greatly in the extracellular N-terminus region of the receptors. The delta, kappa and mu-receptors serve as functional receptors for endogenous enkephalin, dynorphin, and beta-endorphin peptide ligands, respectively, mediating their signal via coupling to Gi/o alpha subunits to inhibit adenylyl cyclases and calcium conductance (N- and L-type channels), and to stimulate MAPK activation and potassium conductance. Delta-opioid receptors are highly expressed in the olfactory bulb, neocortex, caudate putamen and nucleus accumbens, with peripheral expression in the gastro-intestinal tract and vas deferens. Delta-opioid receptors function to inhibit neurotransmitter release resulting in a variety of biological effects including analgesia, motor integration, gastro-intestinal motility, olfaction,

Table of Abbreviations

Abbreviated Name
Opioid Receptor kappa pAb

Species Reactivity
H, M, R

Applications
WB, Membrane ELISA

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of mouse Opioid Receptor kappa

Host
Rabbit

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For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Goat anti-Rabbit IgG Polyclonal Antibody, HRP
 		SAB-300
Opioid Receptor delta Polyclonal Antibody
 		905-745-100
Opioid Receptor µ Polyclonal Antibody
 		905-744-100

Citations
Launch Citation Database

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