Cannabinoid Receptor 2 (CB2) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
Cannabinoid Receptor 2 (CB2) Polyclonal Antibody 100 µL  905-749-100 $295.00
Background
The cannabinoid receptors CB1 and CB2 are GPCRs named for their signaling function in response to cannabinoid drugs such as Delta9-tetrahydrocannabinol (Delta9-THC). In addition to Delta9-THC and its synthetic analogs, CB1 and CB2 receptors are bound by endogenous eicosanoid ligands (e.g. anandamide), and signal via Gi/o alpha subunits to regulate adenylyl cyclase activity (generally inhibitory), ion channel activation, intracellular Ca2+ levels, nitric oxide synthase activation, and immediate early gene expression. CB1 and CB2 signals in turn regulate neurological and immunological functions such as inhibition of neurotransmitter release and immune cell migration, antigen processing, and cytokine production.

Table of Abbreviations

Applications
IHC, WB, Membrane ELISA

Product Image(s): click to enlarge

Species Reactivity
R

Format
PBS, 50% glycerol, 0.01% sodium azide

Host Species
rabbit

Immunogen
Synthetic peptide derived from a sequence on the amino-terminus of rat Cannabinoid receptor 2

Purification Method
Peptide Affinity

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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