Angiotensin II Type-1 Receptor Polyclonal Antibody

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Description Size Catalog# Price Quantity  
Angiotensin II Type-1 Receptor Polyclonal Antibody 100 µL  905-743-100 $295.00
Background
The actions of the octapeptide circulatory hormone angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane domain-containing GPCR family. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II in cardiovascular homeostasis. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing.

Table of Abbreviations

Conjugate

Applications
IHC, WB, ELISA

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Species Reactivity
H, M, R

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of human Angiotensin II Receptor (AT1)

Host
Rabbit

Clone Number
not applicable

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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