Dopamine Receptor (D2) Polyclonal Antibody

Brand: Proteimax Print Page
Description Size Catalog# Price Quantity  
Dopamine Receptor (D2) Polyclonal Antibody 100 µg  905-740-100 $295.00
Background
Dopamine is the predominant catecholamine neurotransmitter in the mammalian brain, where it regulates locomotor, emotional, memory, and dietary intake functions, as well as peripheral roles such as hormone secretion and renal function. Dopamine receptors (D1-D5) are members of the seven transmembrane domain containing GPCR family, and are the target of several anti-psychosis and anti-Parkinsonian drugs. The D2, D3, and D4 receptors signal via coupling of Gi/Go alpha G-protein subunits to inhibit adenylyl cyclase activity and modulate cellular potassium and calcium ion channel conductance. Expression of the D2 receptor is found primarily in the brain (striatum, olfactory tubercle, and nucleus accumbens) and in the anterior and intermediate lobes of the pituitary.

Table of Abbreviations

Conjugate

Species Reactivity
H, M, R

Applications
IHC, WB, Membrane ELISA, Cellular ELISA

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of mouse Dopamine Receptor (D2)

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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