PGE2 CLIA Kit

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Description Size Catalog# Price Quantity  
PGE2 CLIA Kit 1x96 well  910-001 $345.00
Background
Prostaglandin E2 is formed in a variety of cells from PGH2, which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGH2 has been shown to have a number of biological actions, including vasodilation, both anti- and pro-inflammatory action, modulation of sleep/wake cycles, and facilitation of the replication of human immunodeficiency virus. PGE2 elevates cAMP levels, stimulates bone resorption, and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.

Table of Abbreviations

Product Comments
The Prostaglandin E2 CLIA kit is a competitive immunoassay for the quantitative sensitive determination of Prostaglandin E2 in biological fluids. Sample types include culture media, human saliva, serum, and urine.

Applications
EIA

Format
ELISA

Features

  • Validated in numerous sample matrices
  • Results in just 3 hours
  • Sensitive to 6.03 pg/mL

Range
7.81 - 1,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
PGE2 100%
PGE1 70.0%
PGE3 16.3%
PGF1alpha 1.40%
PGF2alpha 0.70%
6-keto-PGF1alpha 0.60%
PGA2 0.10%
PGB1 0.10%
<0.10%: 13,14-dihydro-15-keto-PGF2alpha / 6,15-keto-13,14-dihydro-PGF1alpha / Thromboxane B2 / 2-Arachidonoylyglycerol / Anandamide / PGD2 / Arachidonic Acid

Sample Types
culture media, saliva, serum, urine, whole blood

Samples Per Kit
36 in duplicate per 96 well kit

Sensitivity
6.03 pg/mL

Significance and Uses
Prostaglandin E2 (PGE2) is formed from PGH2 which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. Prostaglandin E2 has been shown to have a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles and of the replication of human immuno deficiency virus. Prostaglandin E2 also elevates cyclic AMP levels, stimulates bone resorption and has thermoregulatory effects. In addition, Prostaglandin E2 has been shown to be a regulator of sodium excretion and renal hemodynamics.

Species Reactivity
Species Independent

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Ordering Info
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