LTB4 EIA Kit

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Description Size Catalog# Price Quantity  
LTB4 EIA Kit  1x96 well 900-068 $345.00  
LTB4 EIA Kit  5x96 well 901-068 $1,395.00  
Background
Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.

Table of Abbreviations

Applications
EIA

Format
ELISA

Features

  • Validated in many matrices
  • Results in 4 hours

Range
11.7 - 3,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
LTB4 100%
6-trans-12-epi-LTB4 5.50%
6-trans-LTB4 4.90%
12-epi-LTB4 0.94%
<0.20%:20-OH-LTB4 / PGE2 / PGF2alpha / 20-COOH-LTB4 / LTC4 / LTD4 / LTE4 / 5(S)-HETE / 12(S)-HETE / 15(S)-HETE

Sample Types
culture media, saliva, urine, EDTA plasma

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
5.63 pg/mL

Species Reactivity
Species Independent

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
LTB4 EIA Kit 900-068   Kit Insert    MSDS   
LTB4 EIA Kit 901-068   Kit Insert    MSDS   

Related Products

Product Name Catalog#
12(S)-HETE EIA Kit
 		900-050
12(S)-HETE EIA Kit
 		901-050
13(S)-HODE EIA Kit
 		900-108
15(S)-HETE EIA Kit
 		900-051
15(S)-HETE EIA Kit
 		901-051
Creatinine Colorimetric Detection Kit
 		907-030
Cysteinyl Leukotriene EIA Kit
 		900-070
PGE2 EIA Kit
 		900-001
sPLA2 Activity Kit
 		907-002

Citations
Launch Citation Database

Ordering Info
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