Complement component C3a/C3a desArg (human)

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Description Size Catalog# Price Quantity  
Complement component C3a/C3a desArg (human)  100 µg GAU 017-01B-01 $685.00  
Background
Activation of the complement cascade is initiated by multiple pathways, including C1q binding of antigen-antibody complexes on pathogens (classical pathway), binding of serum lectin to pathogen-unique mannose residue patterns (MBL pathway), or the spontaneous hydrolysis of C3 and subsequent processing to C3 convertase (alternative pathway). C3a and C4a are two complement cleavage products of 77- and 76-amino acid residues, respectively, that are liberated into the bloodstream and processed to their more stable metabolites C3a des Arg and C4a des Arg. Although both fragments have anaphylactic properties, C3a is considered a more potent stimulator of smooth muscle cell contraction, histamine release, and inflammation than C4a. Complement activation is associated with sepsis, respiratory distress syndrome, multi-organ failure, and transplant organ rejection.

Table of Abbreviations

Conjugate
Biotin

Species Reactivity
H

Isotype
IgG1

Applications
EIA, WB

Purification
Protein A/G Affinity

Immunogen
(see spec sheet)

Host
Mouse

Clone Number
not available

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Complement component C3a/C3a desArg (human) GAU 017-01B-01  

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Citations
Launch Citation Database

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