Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody

Brand: BioPorto-AntibodyShop Print Page
Description Size Catalog# Price Quantity  
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody  50 µg HAV 004-01-S $145.00  
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody  200 µg HAV 004-01-02 $430.00  
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody  1 mg HAV 004-01-1 $1,970.00  
Background
Activation of the complement cascade is initiated by multiple pathways, including C1q binding of antigen-antibody complexes on pathogens (classical pathway), binding of serum lectin to pathogen-unique mannose residue patterns (MBL pathway), or the spontaneous hydrolysis of C3 and subsequent processing to C3 convertase (alternative pathway). C3a and C4a are two complement cleavage products of 77- and 76-amino acid residues, respectively, that are liberated into the bloodstream and processed to their more stable metabolites C3a des Arg and C4a des Arg. Although both fragments have anaphylactic properties, C3a is considered a more potent stimulator of smooth muscle cell contraction, histamine release, and inflammation than C4a. Complement activation is associated with sepsis, respiratory distress syndrome, multi-organ failure, and transplant organ rejection.

Table of Abbreviations

Abbreviated Name
Complement Component C3 mAb

Conjugate

Shipping Information
Please allow 1-2 weeks for delivery.

Species Reactivity
H

Applications
EIA, WB

Isotype
IgG2a

Purification
Protein A/G Affinity

Immunogen
(see spec sheet)

Host
Mouse

Clone Number
not available

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody HAV 004-01-S  
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody HAV 004-01-02  
Complement Component C3 (beta-chain genetic variant, human) Monoclonal Antibody HAV 004-01-1  

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Citations
Launch Citation Database

Ordering Info
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