Complement C4a des Arg (human) EIA Kit

Applications
EIA

Format
ELISA

Features

• Non-radioactive measurement of C4a des Arg
• Sample prep reagents are provided

Range
0.78 - 200 ng/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
C4a des Arg 100%
C4 2.14%
C5a des Arg 0.28%
C3 0.23%
C3a des Arg 0.04%
C5 0.02%

Sample Types
plasma

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
0.76 ng/mL

Significance and Uses
The human Complement C4a des Arg TiterZymeż Enzyme Immunoassay Kit is used for the quantitative determination of levels of the human anaphylatoxin C4a in biological samples. The blood complement system has a variety of defense mechanisms against microbial and viral infections. Complement C4a is a peptide derived from the glycoprotein C4 during activation of the complement system by the classical or the alternative pathway. The C4a anaphylatoxin is very short-lived and in serum is cleaved into the stable C4a des Arg. Quantitation of the des Arg metabolite allows reliable conclusions about complement activation in test samples. Activation of the complement system occurs during sepsis, respiratory distress syndrome, multi-organ failure and in transplant organ rejection.

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.