Aconitase (ACO1) Monoclonal Antibody (2C1)

Brand: Abnova (sold only in the US or Canada) Print Page
Description Size Catalog# Price Quantity  
Aconitase (ACO1) Monoclonal Antibody (2C1) 100 ug  H00000048-M01 $285.00
Background
Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

Table of Abbreviations

Species Reactivity
H

Isotype
IgG2a

Clone
2C1

Applications
EIA

Purification
Protein A Affinity

Tag
GST

Shipping Information
Please allow 1-2 weeks for delivery.

Immunogen
Mouse monoclonal antibody raised against a partial recombinant ACO1.

Spec Sheet
View Spec Sheet

Related Diseases
Not available

Host
Mouse

For research use only, not for diagnostic or therapeutic use.

Documentation

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Citations
Launch Citation Database

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