Endothelin-1 (human) EIA Kit

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Description Size Catalog# Price Quantity  
Endothelin-1 (human) EIA Kit 1x96 well  900-020 $450.00
Background
Endothelins (ET) are isopeptides produced by vascular endothelium that have potent vasoconstrictive activity. The peptides are encoded by three separate genes and processed to yield 39-residue "Big ET" molecules which are further processed to the 21 amino acid sequences designated ET-1, ET-2 and ET-3. ET action is mediated via binding to two receptors, ETA and ETB. Activation of ETA increases vasoconstriction and sodium retention, thereby increasing blood pressure. Activation of ETB receptors triggers the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells and increases urine production and elimination, thereby lowering blood pressure.

Table of Abbreviations

Applications
EIA

Features

  • Non-radioactive determination of ET-1
  • Results in just 2 hours
  • Convenient 4°C storage

Range
0.78 - 100 pg/mL

Sample Size
100 µL

Cross Reactivities
ET-1 100%... ET-2, ET-3, Big ET-1, Big ET-2, Big ET-3 < 0.1%

Sample Types
culture supernates, serum, plasma

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
0.14 pg/mL

Species Reactivity
H, M, R, B, C, P, RB

Time To Answer
Overnight

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert
MSDS
Technical Bulletin

Related Products

Product Name Catalog#
Endothelin-A (ET-A) Receptor Polyclonal Antibody
 		915-006
Endothelin-A (ET-A) Receptor Polyclonal Antibody
 		915-007
Endothelin-B (ET-B) Receptor (B27) Polyclonal Antibody
 		915-008

Citations
Launch Citation Database

Ordering Info
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