eEF2 (phospho-Thr56) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
eEF2 (phospho-Thr56) Polyclonal Antibody 100 µg  905-775-100 $295.00
Background
Eukaryotic elongation factor 2 (eEF2) mediates the GTP-dependent translocation of nascent peptides from the A-site to the P-site of the ribosome relative to mRNA after addition of each amino acid to the nascent chain. Phosphorylation of eEF2 within the GTPbinding domain at Thr56 by eEF2 kinase inactivates eEF2 and results in the termination of mRNA translation. Conversely, eEF2-regulated protein synthesis can be stimulated by dephosphorylation of eEF2 at Thr56 by protein phosphatases such as PP2A, and/or by upstream kinase inactivation via the mTOR pathway.

Table of Abbreviations

Conjugate

Applications
WB

Isotype
not applicable

Purification
Peptide Affinity

Species Reactivity
H, M, R

Immunogen
Synthetic phospho-peptide derived from human eEF2

Host
Rabbit

Clone Number
not applicable

Positive Control
LYC-3T100

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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