Rictor Monoclonal Antibody (1G11)

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Description Size Catalog# Price Quantity  
Rictor Monoclonal Antibody (1G11) 100 µg  905-766-100 $398.00
Background
The mTOR (mammalian target of rapamycin) pathway coordinates nutrient signals with growth factor dependent signaling. mTOR is organized in two independent protein complexes, mTORC1 and mTORC2. The mTORC1 complex containing mTOR, GbetaL/mLST8 and Raptor is sensitive to rapamycin, while the mTORC2 complex containing mTOR, GbetaL/mLST8, SIN1, and Rictor is rapamycin insensitive. The mTOR/Rictor complex phosphorylates numerous substrates associated with regulation of the actin cytoskeleton, and is also responsible for phosphorylation of Akt/PKB at Ser473, a critical step in Akt activation.

Table of Abbreviations

Applications
WB

Product Image(s): click to enlarge

Species Reactivity
H, M, R

Format
Lyophilized from 2x PBS, 0.09% sodium azide, PEG, and sucrose

Host Species
mouse

Immunogen
Synthetic peptide derived from the sequence of Rictor, conjugated to hemocyanin

Positive Control
HeLa Cell Lysates LYC-HL100

Purification Method
Ultrafiltration and size exclusion chromatography

Clone
1G11

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Raptor Monoclonal Antibody (10E10)
 		905-765-100
mTOR Polyclonal Antibody
 		905-687-100

Citations
Launch Citation Database

Ordering Info
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