Insulin Receptor beta Monoclonal Antibody (C18C4)

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Description Size Catalog# Price Quantity  
Insulin Receptor beta Monoclonal Antibody (C18C4) 100 µg  905-683-100 $295.00
Background
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Table of Abbreviations

Abbreviated Name
Insulin Receptor beta mAb (C18C4)

Conjugate

Applications
WB

Isotype
IgG1

Product Image(s): click to enlarge

Purification
Protein G Affinity

Immunogen
Recombinant cytoplasmic domain of human Insulin Receptor beta

Host
Mouse

Clone Number
C18C4

Positive Control
Human (MCF-7), rat (Rat-2), and mouse (L-929)

Species Reactivity
H, M, R, B, HA, P, S, RB

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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