Table of Abbreviations
Applications
EIA
Format
ELISA
Features
- The first commercially available Hsp70 assay on the market
- Hundreds of publications in peer-reviewed journals
- Suitable for cell and tissue extracts
Range
780 - 50,000 pg/mL
Cross Reactivities
Specific for both natural source and recombinant inducible Hsp70. The assay does not cross react with 5,000ng/mL of bovine constitutive Hsc70, recombinant hamster Grp78, E. coli DnaK, or recombinant M. tuberculosis Hsp71.
Sample Size
100µL/well
Product Image(s): click to enlarge
Sample Types
cell lysates, and tissue extracts
Samples Per Kit
40 samples in duplicate per 96 well kit
Sensitivity
200 pg/mL
Significance and Uses
Inducible heat shock protein 70 (Hsp70) is a stress protein whose expression is upregulated when the cell or organism is placed under conditions of stress. Hsp70 is essential for cellular recovery, survival and maintenance of normal cellular function. It is also a molecular chaperone that prevents protein aggregation and refolds damaged proteins in response to cellular stress caused by environmental insults, pathogens and disease. Current research is aimed at exploiting Hsp70's cellular protective abilities as a therapeutic strategy against damaging cellular stress.
Species Reactivity
H, M, R
Time To Answer
4.5 hours
For research use only, not for diagnostic or therapeutic use.
Ordering Info
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