Tunicamycin, N-linked glycosylation Inhibitor

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Description Size Catalog# Price Quantity  
Tunicamycin, N-linked glycosylation Inhibitor 10 mg   908-297 $85.00
Background
Tunicamycin is an inhibitor of the UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosamine-1-phosphate transferase (GPT), acting to block the initial step of dolichol-linked oligosaccharide biosynthesis. Treatment with tunicamycin blocks the synthesis of asparagine (N)-linked glycoproteins in the ER, and induces expression of binding protein (BiP) as part of the unfolded protein response (UPR).

Table of Abbreviations

Applications
Inhibits protein glycosylation, arrests cell cycle in late G1, unstable at acidic pH, product is not sterile

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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