LY-294002, PI3 Kinase Inhibitor

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
LY-294002, PI3 Kinase Inhibitor 5mg   HPK-106L $105.00
Background
LY-294002 is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI3K). LY-294002 displays an IC50 of 1.4 µM in vitro and inhibits all PI3K isoforms equally. Other kinases such as PKC, PKA, MAP kinase, S6 kinase, EGF receptor tyrosine kinase, c-src kinase, PI 4-kinase, diacylglycerol kinase or rabbit kidney ATPase are not inhibited at 50 µM. LY-294002 induces apoptosis in many cell types by blocking the PI3-K/Akt anti-apoptotic pathway.

Table of Abbreviations

Applications
PI3-K Inhibition

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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