Caspase-13 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Caspase-13 Polyclonal Antibody  100 µg AAP-123E $115.00  
Caspase-13 Polyclonal Antibody  25 µg AAP-123C $255.00  
Background
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Abbreviated Name
Caspase-13 pAb

Conjugate

Applications
WB

Isotype
not applicable

Purification
Ion Exchange

Immunogen
Synthetic peptide derived from the sequence of human Caspase-13

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Caspase-13 Polyclonal Antibody AAP-123E  
Caspase-13 Polyclonal Antibody AAP-123C  

Related Products

Product Name Catalog#

Citations
Launch Citation Database

Ordering Info
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