BMP4 Monoclonal Antibody (26H16)

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Description Size Catalog# Price Quantity  
BMP4 Monoclonal Antibody (26H16) 100 µg   905-757-100 $270.00
Background
Bone morphogenic protein 4 (BMP4) is a member of the TGF-beta superfamily that plays a critical role in mammalian mesenchymal development, influencing hematopoeisis and osteoblast differentiation and function. BMP-4 is secreted as 54 kDa inactive precursor peptides that dimerize and are activated following cleavage by members of the proprotein convertase family. Active BMP-4 binds type I and type II serine/threonine kinase receptors which signal via phosphorylation of Smad family proteins. BMP-4 and the highly homologous BMP-2 are functional orthologues of the decapentaplegic (dpp) gene in Drosophila that regulates embryonic leg and wing imaginal disc patterning and larval gut development.

Table of Abbreviations

Applications
WB

Species Reactivity
H

Conjugate

Isotype
not available

Product Image(s): click to enlarge

Purification
Protein A Affinity

Immunogen
Recombinant full-length human BMP4 expressed in CHO cells

Host
Mouse

Clone Number
26H16

Positive Control
MKN-48 cell lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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