Anthrax Protective Antigen (PA) Monoclonal Antibody (PA6)

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Description Size Catalog# Price Quantity  
Anthrax Protective Antigen (PA) Monoclonal Antibody (PA6) 100 µg   905-619 $270.00
Background
The exotoxin produced by B. Anthracis is composed of three proteins: a cell-receptor binding protein known as Protective Antigen (PA), and two enzymes, Edema Factor (EF) and Lethal Factor (LF). An 83 kDa form of PA binds to a cell surface receptor and, upon proteolytic activation to a 63 kDa fragment, heptamerizes to form a membrane channel that mediates the entry of three molecules of LF or EF into the cells. PA and LF form Lethal Toxin, which is the dominant virulence factor produced by B. Anthracis and is the major cause of death in infected animals.

Table of Abbreviations

Applications
EIA, IP, WB

Species Reactivity
BA

Conjugate

Isotype
IgG1

Purification
Protein G Affinity

Immunogen
Anthrax protective antigen

Host
Mouse

Clone Number
PA6

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#

Citations
Launch Citation Database

Ordering Info
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