BLK Active Recombinant Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
BLK Active Recombinant Protein  5 µg PPK-423Z $298.00  
BLK Active Recombinant Protein  1 µg PPK-423X $98.00  
Background
Blk, also known as B lymphoid kinase, is a 55 kDa tyrosine kinases with SH3, SH2, and catalytic domains that contain consensus sequences of the Src family of protein tyrosine kinases. Blk, which is expressed specifically in the B-cell lineage. Upon activation, the SH2 domain of Blk binds more than 10 distinct phosphoproteins. Blk prefers peptide substrates of the structure I/L-Y-D/E-X-L. These substrates resemble critical features of the ITAM motifs found in elements such as the intracellular components Ig-alpha and Ig-beta of the b cell receptor.

Table of Abbreviations

Species Reactivity
not applicable

Applications
KA

Format
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 30% glycerol

Purity
>90%

Source
Active recombinant full length human BLK containing an N-terminal GST tag, expressed by baculovirus in Sf9 insect cells

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
BLK Active Recombinant Protein PPK-423Z  
BLK Active Recombinant Protein PPK-423X  

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