Chk2 Recombinant Human Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Chk2 Recombinant Human Protein  5 µg PPK-419Z $310.00  
Chk2 Recombinant Human Protein  1 µg PPK-419X $95.00  
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Abbreviated Name
Chk2 Recomb Human Protein

Expression System
Active recombinant full length human CHK2 expressed by baculovirus in Sf9 insect cells.

Species Reactivity
not applicable

Applications
KA

Purification
>90% pure as determined by SDS-PAGE analysis

Tag

Source
Human

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Chk2 Recombinant Human Protein PPK-419Z  
Chk2 Recombinant Human Protein PPK-419X  

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