Dkk-1 Recombinant Mouse Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Dkk-1 Recombinant Mouse Protein   50 µg KPR-CP100D $300.00  
Dkk-1 Recombinant Mouse Protein   200 µg KPR-CP100F $810.00  
Background
Dkk-1 (Dickkopf or Dickkopf-1) is a secreted inhibitor of the Wnt/canonical signaling pathway which mediates a variety of cellular processes. Wnt proteins are extracellular signaling molecules that initiate activation of the canonical pathway by binding low-density lipoprotein receptor-related protein 5&6 (LRP5/6) coreceptors, triggering a cascade of events that stabilize beta-catenin. Wnts mediate osteoblast development and cell-to-cell interactions during embryogenesis, and are also responsible for regulating bone mass in adults during normal bone remodeling processes. Wnts are also found to be expressed during the stationary phase of the cell cycle and are thought to control expansion of bone marrow stromal cells preventing overpopulation in marrow.

Table of Abbreviations

Applications
WB Control

Species Reactivity
Not applicable

Expression System
Mature recombinant mouse Dkk-1 protein with N-terminal his-tag, expressed in E. coli

Purification
> 95% pure as determined by SDS-PAGE and Western Blot analysis

Tag
HIS

Source
Mouse

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_KPR-CP100_LOT-02020902
MSDS
Spec Sheet

Product Manual

Product Name Catalog # Manual
Dkk-1 Recombinant Mouse Protein KPR-CP100D  
Dkk-1 Recombinant Mouse Protein KPR-CP100F  

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Citations
Launch Citation Database

Ordering Info
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