Acetyltransferase Activity Kit

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Description Size Catalog# Price Quantity  
Acetyltransferase Activity Kit 1x96 well  907-026 $385.00
Background
Acetylation is an important covalent molecular modification. Originally identified as the method by which certain bacteria were able to deactivate anti-microbial compounds, acetylation is now also known as an important partitioning and signaling modification. Acetyltransferases are enzymes that covalently transfer an acetyl group from a donor molecule (Acetyl CoA) to an acceptor. Acetyl CoA serves as a universal donor while the acceptor varies with the acetyltransferase. Acceptors include histones, kinases, transcription factors, receptors, neurotransmitter precursors like choline and serotonin, and anti-microbial agents like chloramphenicol and fluoroquinones. Acetylation can signal an increase or decrease in activity based on the context of the message. Frequently located at critical junctions in metabolic pathways, Acetyltransferases and their regulation have become attractive therapeutic targets to treat everything from insomnia to cancer.

Applications
Activity

Format
Fluorometric Activity Kit

Feature

  • Amendable to HTS Applications
  • Measure increase/decrease in Acetyltransferase Activity
  • Universal: Applicable for all AcetylCoA-dependent acetyltransferases
  • Low sample volume required
  • Completely customizable to your needs
  • Positive Control provided
  • Fluorometric dection provides superior sensitivity
  • Highly stable liquid reagents

Product Image(s): click to enlarge

Sample Types
Purified in vitro samples that do not contain reductants

Species Reactivity
Species Independent

Time to Answer
< 1 hour (Endpoint assay option); Kinetic assay option is dependenent upon samples

For research use only, not for diagnostic or therapeutic use.

Documentation
Acetyltransferase Poster (1.3 MB)
Assay Layout
Kit Insert
MSDS

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Citations
Launch Citation Database

Ordering Info
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