Corticosterone EIA Kit

Product Comments
The Corticosterone kit is a competitive immunoassay for the quantitative determination of corticosterone in biological samples. Sample types include culture media, saliva, serum, and heparin plasma.

Applications
EIA

Format
ELISA

Features

• Low cross reactivity to other steroids
• Highly cited in peer reviewed literature

Range
32 - 20,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
Corticosterone 100%
Deoxycorticosterone 28.6%
Progesterone 1.7%
Testosterone 0.13%
Tetrahydrocorticosterone 0.28%
Aldosterone 0.18%
Cortisol 0.046%
< 0.03%: Pregnenolone / beta-Estradiol / Cortisone / 11-dehydrocorticosterone acetate

Sample Types
culture media, saliva, serum, hep plasma, rhinoceros feces, mouse feces

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
27.0 pg/mL

Significance and Uses
Corticosterone (also referred to as Kendall's Compound B and Reichstein Substance B) is a glucocorticoid secreted by the cortex of the adrenal gland. Corticosterone is produced in response to the stimulation of the adrenal cortex by adrenocorticotropic hormone (ACTH) and is the precursor of aldosterone. Corticosterone is a major indicator of stress since stress increases the production of corticosteroids. Studies involving corticosterone and levels of stress include impairment of long term memory retrieval, chronic corticosterone elevation due to dietary restrictions and in response to burn injuries. In addition to stress levels, corticosterone is believed to play a decisive role in sleep-wake patterns.

Species Reactivity
Species Independent

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.