Complement C3a des Arg (human) EIA Kit

Applications
EIA

Format
ELISA

Features

• Non-radioactive measurement of C3a des Arg
• Sample prep reagents are provided

Range
0.313 - 20 ng/mL

Sample Size
100 µL

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Cross Reactivities
C3a des Arg 100%
C3 1.28%
C4a des Arg 0.40%
C4 0.31%
C5a des Arg 0.10%
C5 0.05%

Sample Types
EDTA plasma

Samples Per Kit
37 in duplicate per 96 well kit

Sensitivity
0.120 ng/mL

Significance and Uses
The human Complement C3a des Arg Correlate-EIATM is used for the quantitative determination of levels of the human anaphylatoxin C3a in biological samples. The blood complement system has a variety of defense mechanisms against microbial and viral infections. Complement C3a is a peptide derived from the glycoprotein C3 during activation of the complement system by the classical or the alternative pathway. The C3a anaphylatoxin is very short-lived and in serum is cleaved immediately into the more stable C3a des Arg. Quantitation of the des Arg metabolite allows reliable conclusions about complement activation in test samples. Activation of the complement system occurs during sepsis, respiratory distress syndrome, multi-organ failure and in transplant organ rejection.

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.