15-deoxy-delta12,14-PGJ2 EIA Kit

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Description Size Catalog# Price Quantity  
15-deoxy-delta12,14-PGJ2 EIA Kit   1x96 well 900-023 $360.00  
15-deoxy-delta12,14-PGJ2 EIA Kit   5x96 well 901-023 $1,440.00  
Background
15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).

Normalize urine samples to creatinine with our Creatinine Colorimetric Detection Kit.

Table of Abbreviations

Applications
EIA

Species Reactivity
Species Independent

Features

  • Only 15d-PGJ2 immunoassay kit on the market
  • Much easier than GC/MS

Range
195 - 200,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
15-deoxy-Delta12,14-PGJ2 100%
PGJ2 49.2%
Delta12-PGJ2 5.99%
PGD2 4.92%
Arachidonic Acid 0.03%
<0.01%: PGF2alpha / 9alpha,11beta-PGF2alpha / PGE2 / Thromboxane B2 / 2-Arachidonoylglycerol / Anandamide

Sample Types
culture media, saliva, urine, plasma

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
36.8 pg/mL

Time To Answer
5 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
Kit Insert
AssayLayout

Product Manual

Product Name Catalog # Manual
15-deoxy-delta12,14-PGJ2 EIA Kit 900-023   Kit Insert     MSDS    
15-deoxy-delta12,14-PGJ2 EIA Kit 901-023   Kit Insert     MSDS    

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Citations
Launch Citation Database

Ordering Info
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