Hip Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hip Polyclonal Antibody  50 µL SPA-766D $160.00  
Hip Polyclonal Antibody  200 µL SPA-766F $340.00  
Background
Hip (Hsc70-interacting protein) is a cytosolic protein that exists as a homo-oligomer and participates in the regulation of Hsc70 in eukaryotic cells. Hip interacts with the ATPase domain of Hsc70 molecules through its tetratricopeptide repeats and flanking charged alpha-helices. Upon binding to Hsc70, Hip stabilizes the ADP-bound state of Hsc70, a conformation that has a high affinity for unfolded substrate proteins. Together with Hsp40 and BAG-1, Hip may regulate the chaperone activity of Hsc70 by stabilizing the chaperone-substrate complex.

Table of Abbreviations

Applications
WB

Format
PBS, pH 7.2, 0.09% azide, 50% glycerol

HostSpecies
rabbit

Immunogen
Recombinant rat Hip protein

Species Reactivity
H, M, R, B

Purification Method
Protein A Affinity

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
TechSpec

Product Manual

Product Name Catalog # Manual
Hip Polyclonal Antibody SPA-766D  
Hip Polyclonal Antibody SPA-766F  

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