BAG-1 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
BAG-1 Polyclonal Antibody 100 µg  905-735-100 $255.00
Background
Bag-1 is a multifunctional Bcl-2-binding protein that lacks sequence homology with Bcl-2 and its related proteins, and functions to enhance the anti-apoptotic effects of Bcl-2. Bag-1 binds to the intracellular domain of the hepatocyte growth factor (HGF) and platelet-derived growth factor (PDGF) receptors, enhancing growth factor mediated protection from apoptosis. Bag-1 is known to modulate the chaperone activity of Hsc70/Hsp70, serving as a nucleotide exchange factor via binding to the ATPase domain of Hsc70/Hsp70. Bag-1 is known to promote cell survival through activation of the Raf-1 kinase.

Table of Abbreviations

Conjugate

Applications
WB

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Species Reactivity
H, M, R

Immunogen
Synthetic peptide corresponding to sequence near the carboxy-terminus of human BAG-1

Host
Rabbit

Clone Number
not applicable

Positive Control
PC-3 Cell Lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Bag-1 Monoclonal Antibody (4A2)
 		AAM-400E
Bcl-2 Monoclonal Antibody (83-8B)
 		AAM-072E
Hsc70 (Hsp73) Polyclonal Antibody
 		SPA-816
Hsp70 (Hsp72) Polyclonal Antibody
 		SPA-812

Citations
Launch Citation Database

Ordering Info
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