Hip Recombinant Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hip Recombinant Protein 100 µg  SPP-767E $350.00
Background
Hip (Hsc70-interacting protein) is a cytosolic protein that exists as a homo-oligomer and participates in the regulation of Hsc70 in eukaryotic cells. Hip interacts with the ATPase domain of Hsc70 molecules through its tetratricopeptide repeats and flanking charged alpha-helices. Upon binding to Hsc70, Hip stabilizes the ADP-bound state of Hsc70, a conformation that has a high affinity for unfolded substrate proteins. Together with Hsp40 and BAG-1, Hip may regulate the chaperone activity of Hsc70 by stabilizing the chaperone-substrate complex.

Table of Abbreviations

Species Reactivity
not applicable

Applications
WB Control

Format
Recombinant rat Hip protein in 20mM MOPS pH 7.2, 50mM KCl, 2mM MgCl2

Purity
>85% (SDS-PAGE)

Source
Recombinant rat (brain) Hip fusion protein is expressed in E. coli .

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Related Products

Product Name Catalog#
Hip Polyclonal Antibody
 		SPA-766

Citations
Launch Citation Database

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