Hsc70 (Hsp73) (ATPase Fragment) Recombinant Bovine Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsc70 (Hsp73) (ATPase Fragment) Recombinant Bovine Protein  100 µg SPP-752E $325.00  
Hsc70 (Hsp73) (ATPase Fragment) Recombinant Bovine Protein  20 µg SPP-752B $120.00  
Background
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Abbreviated Name
Hsc70 (Hsp73) (ATPase Frag) Recomb Bovine Protein

Expression System
Recombinant bovine Hsc70 ATPase fragment expressed in E. coli.

Species Reactivity
not applicable

Applications
AA

Purification
Multi-step chromatography

Source
Bovine

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Hsc70 (Hsp73) (ATPase Fragment) Recombinant Bovine Protein SPP-752E  
Hsc70 (Hsp73) (ATPase Fragment) Recombinant Bovine Protein SPP-752B  

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Hsc70 (Hsp73) Recombinant Bovine Protein
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Citations
Launch Citation Database

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