17-AAG

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
17-AAG 1mg  HPK-101J $265.00
Background
17-AAG is a less toxic and more stable analog of geldanamycin. It is an HSP-90 inhibitor that displays a 100-fold higher affinity for HSP-90 derived from tumor cells compared to HSP-90 from normal cells. 17-AAG inhibits Akt activation and expression in tumors and synergizes with a number of antitumor agents such as taxol, cisplatin, and UCN-01. 17-AAG causes the inactivation, destabilization and eventual degradation of HIF-1alpha.

Table of Abbreviations

Species Reactivity
Species Independent

Applications
Hsp90 Inhibition

Format
Lyophilized

Purity
0.98

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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Citations
Launch Citation Database

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