eNOS Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
eNOS Polyclonal Antibody  50 µg KAP-NO023D $125.00  
eNOS Polyclonal Antibody  200 µg KAP-NO023F $305.00  
Background
The diffusible free radical gas nitric oxide (NO) affects a variety of physiological functions, and is a key regulator of the cardiovascular, nervous, and immune systems. NO is synthesized in many tissues from L-arginine, oxygen, and NADPH by three known isoforms of a heme-containing flavoprotein termed NO synthase (NOS-I/nNOS, NOS-II/iNOS, and NOS-III/eNOS). eNOS is a constitutively expressed isoform originally characterized in vascular endothelium. eNOS is activated by the interplay of eNOS binding proteins such as calmodulin and Hsp90, as well as by posttranslational modification of the protein by phosphorylation at multiple sites including Ser1177 (activating) and Thr495 (inhibiting). eNOS activation at Ser1177 can be triggered by many protein kinases including Akt/PKB, PKA, CAMKII, or by dephosphorylation of Thr495 by phosphatases such as PP2A.

Table of Abbreviations

Abbreviated Name
eNOS pAb

Purification
Peptide Affinity

Applications
WB

Immunogen
Synthetic peptide derived from the sequence near the carboxyterminus of human eNOS.

Host
Rabbit

Product Image(s): click to enlarge

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
Spec Sheet

Product Manual

Product Name Catalog # Manual
eNOS Polyclonal Antibody KAP-NO023D  
eNOS Polyclonal Antibody KAP-NO023F  

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Citations
Launch Citation Database

Ordering Info
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