Osteopontin (mouse) EIA Kit

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Description Size Catalog# Price Quantity  
Osteopontin (mouse) EIA Kit 1x96 well  900-090 $460.00
Background
Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to be a positive indicator of colon and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

Table of Abbreviations

Applications
EIA

Features

  • Results in just 2 hours
  • Sensitive to 192 pg/mL

Range
1,000 - 64,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
mouse Osteopontin 100%
rat Osteopontin 14.8%
human Osteopontin 4.3%

Sample Types
culture media, EDTA plasma, urine

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
192.3 pg/mL

Species Reactivity
M

Time To Answer
2 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

Related Products

Product Name Catalog#
Creatinine Colorimetric Detection Kit
 		907-030
Osteopontin (human) EIA Kit
 		900-142
Osteopontin (rat) EIA Kit
 		900-089

Citations
Launch Citation Database

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