TNF-alpha (rat) EIA Kit

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Description Size Catalog# Price Quantity  
TNF-alpha (rat) EIA Kit 1x96 well  900-086 $495.00
Background
Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

Table of Abbreviations

Applications
EIA

Format
ELISA

Features

  • Immunoassay method much easier than Western blotting

Range
390.6 - 25,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
rat TNF-alpha 100%

Sample Types
culture media, serum

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
420.7 pg/mL

Species Reactivity
R

Time To Answer
2 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

Related Products

Product Name Catalog#
TNF-alpha (human) EIA Kit
 		900-099
TNF-alpha (mouse) EIA Kit
 		900-047

Citations
Launch Citation Database

Ordering Info
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