TNF-alpha (human) EIA Kit

Brand: Assay Designs

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Description	Size	Catalog#	Price	Quantity
TNF-alpha (human) EIA Kit	1x96 well	900-099	$415.00

Background

Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

Table of Abbreviations

Applications
EIA

Features

Stable color coded reagents
Sensitive to 8.4 pg/mL

Range
15.63 - 1,000 pg/mL

Sample Size
100 無

Product Image(s): click to enlarge

Cross Reactivities
human TNF-alpha 100%
Unaffected by: human TNF-beta / human sTNF RI / human sTNF RII / mouse TNF-alpha / mouse sTNF RI / mouse sTNF RII / rat TNF-alpha / porcine TNF-alpha

Sample Types
culture media, serum, EDTA plasma

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
8.43 pg/mL

Species Reactivity
H

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

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Citations
Launch Citation Database

Ordering Info
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TNF-alpha (human) EIA Kit