TNF-alpha (mouse) EIA Kit

Brand: Assay Designs

Print Page

Description	Size	Catalog#	Price	Quantity
TNF-alpha (mouse) EIA Kit	1x96 well	900-047	$405.00

Background

Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

Table of Abbreviations

Applications
EIA

Features

Stable color coded reagents

Range
15.63-2,000 pg/mL

Sample Size
50 無

Product Image(s): click to enlarge

Cross Reactivities
mouse TNF-alpha 100%
Unaffected by mouse: IL-1alpha / IL-1beta / IL-2 / IL-3 / IL-4 / IL-5 / IL-6 / IL-7 / IL-10 / GM-CSF / IFN-gamma / human TNF-alpha / rat TNF-alpha

Sample Types
culture media, serum

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
3.9 pg/mL

Species Reactivity
M

Time To Answer
5 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

Related Products

Product Name	Catalog#
ADAM17/TACE (CT) Polyclonal Antibody	905-249
IKK epsilon Polyclonal Antibody	KAP-TF131E
Interferon-gamma (mouse) EIA Kit	900-137
Interleukin-10 (mouse) EIA Kit	900-148
Interleukin-1beta (mouse) EIA Kit	900-132
Interleukin-6 (mouse) EIA Kit	900-045
SODD (NT) Polyclonal Antibody	905-243
Stop Solution 2, 10 mL	80-0377
TLR4 (MD-2 Complex) Monoclonal Antibody (MTS510), FITC	CSA-805FI
TNF Receptor 2 (TNF-R2) Polyclonal Antibody	905-593
TNF-alpha (human) EIA Kit	900-099
TNF-alpha (rat) EIA Kit	900-086A
Wash Buffer Concentrate, 100 mL	80-1287

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134

Browse by

TNF-alpha (mouse) EIA Kit