cyclic AMP (AM74) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
cyclic AMP (AM74) Polyclonal Antibody 100 µL  915-053 $285.00
Background
Adenosine 3', 5'-cyclic monophosphate (cyclic AMP; cAMP) is one of the most important "second messengers" involved as a modulator of physiological processes. cAMP is also involved in regulating neuronal, glandular, cardiovascular, immune and other functions and actions. A number of hormones are known to activate cAMP through the action of the enzyme adenylate cyclase which converts ATP to cAMP. These hormones include a variety of anterior pituitary peptide hormones such as corticotropin (ACTH), glucagon, calcitonin, thyroid stimulating hormone (TSH) and luteinizing hormone (LH). cAMP has been shown to be involved in the cardiovascular, nervous system, and immune mechanisms, cell growth and differentiation, and general metabolism. There remains considerable interest in the measurement of intracellular cAMP in tissues and cell cultures, and this may help to provide an understanding of the physiology and pathology of many disease states.

Applications
EIA

Species Reactivity
Species Independent

Format
1.0 mg/mL Rabbit IgG in PBS with 0.1% NaN3.

HostSpecies
rabbit

Immunogen
cAMP conjugated to a protein carrier molecule

Isotype
Rabbit IgG

PurificationMethod
Sodium sulfate precipitation

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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