15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody 100 µL  915-043 $345.00
Background
15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).

Table of Abbreviations

Applications
EIA

Format
1.0 mg/mL Rabbit IgG in PBS with 0.1% NaN3.

HostSpecies
rabbit

Immunogen
15-deoxy-D12,14-Prostaglandin J2

Isotype
Rabbit IgG

PurificationMethod
Sodium sulfate precipitation

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Related Products

Product Name Catalog#
15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody
 		915-044

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134