6-keto PGF1alpha Polyclonal Antibody

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Description Size Catalog# Price Quantity  
6-keto PGF1alpha Polyclonal Antibody lyoph  905-028 $115.00
Background
Prostacyclin (PGI2) is involved in platelet aggregation, vasoconstriction, and reproductive functions. However, PGI2 has a half life of 60 minutes in plasma but only 2 to 3 minutes in buffer. The production of PGI2 is typically monitored by measurement of 6-keto-PGF1alpha. 6-keto-PGF1alpha is produced by the nonenzymatic hydration of PGI2, and has been shown to be stable. A number of pharmaceuticals alter and/or inhibit the synthesis of PGI2. Methods to measure PGI2 in blood and urine typically involve HPLC, gas chromatography/mass spectrometry, radioimmunoassay, or enzyme immunoassay.

Species Reactivity
Species Independent

Applications
EIA

Format
antisera

Cross Reactivities
6-keto-PGF1a 100%
PGF1a 7.80%
6-keto-PGE1 6.80%
PGF2a 2.20%
PGE1 0.70%
PGE2 0.60%
<0.01%: PGA1, PGA2, PGB1, PGB2, PGD2, TXB2, 13,14-dihydro-15-keto-PGF2a, 13,14-dihydro-15-keto-PGE2, 15-keto-PGF2a, 15-keto-PGE2

HostSpecies
rabbit

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Related Products

Product Name Catalog#

Citations
Launch Citation Database

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