2,3-dinor-6-keto-Prostaglandin F1alpha Polyclonal Antibody

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Description Size Catalog# Price Quantity  
2,3-dinor-6-keto-Prostaglandin F1alpha Polyclonal Antibody 100 µL  905-004 $255.00
Background
6-keto-PGF1alpha is a stable hydrolysis product of prostacyclin (PGI2). Due to the short half-life of PGI2 in buffer (2-3 minutes) the production of prostacyclin is typically monitored by measurement of the 6-keto-PGF1alpha metabolite and its derivative in urine, 2,3-dinor-6-keto-PGF1alpha. PGI2 has autocoid functions that include platelet aggregation, inhibition of vasoconstrictor responses to pressor hormones, platelet anti- and disaggregatory properties, and reproductive functions. The effects are induced by receptor-mediated elevation of cAMP. Prostacyclin has clinical applications in atherosclerosis and protection from myocardial ischemia.

Table of Abbreviations

Applications
EIA

Format
antisera

Cross Reactivities
2,3-dinor-6-keto--PGF1a 100%
6-keto-PGF1a 89.1%
PGF1a 13.2%
PGF2a 4.99%
13,14-dihydro-PGF1a 2.55%
15-keto-PGF2a 0.32%
PGE1 0.08%
PGD2 0.03%
6,15-diketo-13,14-dihydro-PGF1a 0.03%
PGB1 0.01%
PGE2 0.01%
TXB2 0.01%
PGA2 0.01%

HostSpecies
sheep

Immunogen
2,3-dinor-6-keto-Prostaglandin F1alpha conjugated to bovine serum albumin

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Related Products

Product Name Catalog#
2,3-dinor-6-keto-PGF1 alpha Affinity Resin**
 		RES-110
6-keto PGF1alpha EIA Kit
 		900-004
6-keto PGF1alpha EIA Kit
 		901-004
6-keto-PGF1alpha Polyclonal Antibody
 		905-003
Urinary Prostacyclin EIA Kit
 		900-025
Urinary Prostacyclin EIA Kit
 		901-025

Citations
Launch Citation Database

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