Bmf (NT) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
Bmf (NT) Polyclonal Antibody 100 µg  905-184 $230.00
Background
Bmf (Bcl-2 modifying factor) is a member of the Bcl-2 family of apoptotic proteins. The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the Dynein light chain 2 (DLC2), a component of the myosin V motors, and is sequestered by the cell?s actin cytoskeleton. Disruption of the actin cytoskeleton triggers release and activation of Bmf, initiating the downstream apoptotic program.

Table of Abbreviations

Applications
WB

Product Image(s): click to enlarge

HostSpecies
rabbit

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of human Bmf

PurificationMethod
Affinity purified

Species Reactivity
H, M

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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Product Name Catalog#

Citations
Launch Citation Database

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