Cysteinyl Leukotriene EIA Kit

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Description Size Catalog# Price Quantity  
Cysteinyl Leukotriene EIA Kit  1x96 well 900-070 $345.00  
Cysteinyl Leukotriene EIA Kit  5x96 well 901-070 $1,395.00  
Background
The Cysteinyl Leukotrienes (LTC4, LTD4, and LTE4) are metabolites of arachidonic acid. They are formed via the 5-lipoxygenase pathway by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of Cysteinyl Leukotriene formation. The Cysteinyl Leukotrienes are potent lipid mediators in inflammation. They cause smooth muscle contractions and increased capillary permeability. Monitoring the levels of Cysteinyl Leukotrienes has been useful in several studies, such as Hepatitis B, Helicobacter pylori infections, cerebral vasospasms and blood-brain cell contact, as well as asthma and other inflammatory responses.

Applications
EIA

Format
ELISA

Features

  • Non-radioactive measurement of LTC4/D4/E4

Range
78.1 - 2,500 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
LTC4 100%
LTD4 115.12%
LTE4 62.7%
LTB4 1.16%
Arachidonic Acid 0.61%
PGE2 0.48%
6-trans-LTB4 0.45%
TXB2 0.28%
<0.20%: 20-OH-LTB4 / PGF2alpha / 6-keto-PGF1alpha / PGD2 / 5-HETE / 12-HETE / 15-HETE

Sample Types
culture media, urine

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
26.6 pg/mL

Significance and Uses
The Cysteinyl Leukotriene kit is a competitive immunoassay for the quantitative determination of Cysteinyl Leukotrienes in tissue culture media and urine.

Species Reactivity
Species Independent

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
Cysteinyl Leukotriene EIA Kit 900-070   Kit Insert    MSDS   
Cysteinyl Leukotriene EIA Kit 901-070   Kit Insert    MSDS   

Related Products

Product Name Catalog#
12(S)-HETE EIA Kit
 		900-050
12(S)-HETE EIA Kit
 		901-050
13(S)-HODE EIA Kit
 		900-108
15(S)-HETE EIA Kit
 		900-051
15(S)-HETE EIA Kit
 		901-051
Creatinine Colorimetric Detection Kit
 		907-030
LTB4 EIA Kit
 		900-068
PGE2 EIA Kit
 		900-001

Citations
Launch Citation Database

Ordering Info
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Order by fax: 734-669-0134