LTB4 EIA Kit

Product Comments
The Leukotriene B4 kit is a competitive immunoassay for the quantitative determination of LTB4 in biological fluids. Sample types include culture media, saliva, urine, and EDTA plasma.

Applications
EIA

Format
ELISA

Features

• Validated in many matrices
• Results in 4 hours

Range
11.7 - 3,000 pg/mL

Sample Size
100 µL

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Cross Reactivities
LTB4 100%
6-trans-12-epi-LTB4 5.50%
6-trans-LTB4 4.90%
12-epi-LTB4 0.94%
<0.20%:20-OH-LTB4 / PGE2 / PGF2alpha / 20-COOH-LTB4 / LTC4 / LTD4 / LTE4 / 5(S)-HETE / 12(S)-HETE / 15(S)-HETE

Sample Types
culture media, saliva, urine, EDTA plasma

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
5.63 pg/mL

Significance and Uses
Leukotriene B4 (LTB4) is a major product of arachidonic acid metabolism formed via the 5-lipoxygenase pathway. Leukotriene B4 stimulates leukocyte functions including lysosomal enzyme release, adhesion and aggregation of polymorphonuclear leukocytes. A potent mediator of inflammatory diseases and immunoregulation, Leukotriene B4 also increases the cytotoxic activity of human natural killer cells. Elevated levels of Leukotriene B4 are associated with bronchial vasoconstriction and increased intracellular calcium levels.

Species Reactivity
Species Independent

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.