6-keto PGF1alpha EIA Kit

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Description Size Catalog# Price Quantity  
6-keto PGF1alpha EIA Kit  1x96 well 900-004 $320.00  
6-keto PGF1alpha EIA Kit  5x96 well 901-004 $1,275.00  
Background
6-keto-PGF1alpha is a stable hydrolysis product of prostacyclin (PGI2). Due to the short half-life of PGI2 in buffer (2-3 minutes) the production of prostacyclin is typically monitored by measurement of the 6-keto-PGF1alpha metabolite and its derivative in urine, 2,3-dinor-6-keto-PGF1alpha. PGI2 has autocoid functions that include platelet aggregation, inhibition of vasoconstrictor responses to pressor hormones, platelet anti- and disaggregatory properties, and reproductive functions. The effects are induced by receptor-mediated elevation of cAMP. Prostacyclin has clinical applications in atherosclerosis and protection from myocardial ischemia.

Table of Abbreviations

Abbreviated Name
6-keto PGF1alpha EIA Kit

Applications
EIA

Format
ELISA

Features

  • Results in just 3 hours
  • Convenient 4°C storage
  • Validated in multiple same matrices

Range
3.2 - 50,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
6-keto-PGF1alpha 100%
2.3-dinor-6-keto-PGF1alpha 3.17%
PGF2alpha 1.67%
PGD2 0.60%
PGF1alpha 0.60%
PGE1 0.20%
6.15-diketo-13,14-dihydro-PGF1alpha 0.12%
<0.01%: 13,14-dihydro-15-keto-PGF1alpha, 15-keto-PGF2alpha, PGA2, PGB1, PGE2, Thromboxane B2, 15-Hp-HETE, 2-Arachidonoylglycerol, Anandamide

Sample Types
culture media, saliva, urine, serum

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
1.40 pg/mL

Species Reactivity
Species Independent

Time To Answer
< 3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
6-keto PGF1alpha EIA Kit 900-004   Kit Insert    MSDS   
6-keto PGF1alpha EIA Kit 901-004   Kit Insert    MSDS   

Ordering Info
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